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Similarly, the weighted median estimates for class.Bacteroidia and genus.LachnospiraceaeUCG008 presented suggestive associations with PBC, while the Wald ratio estimate of genus.Lachnospira presented a suggestive association with PBC

177 Recent studies have found that the interactions between gut microbiota and their metabolites, especially TMAO, and autophagy not only regulate intestinal epithelial function and gut homeostasis but also play a role in regulating physiological functions in distant organs

Critically, it does not bind the GH receptor in the same way as full-length GH, so it does not elevate IGF-1 or affect glucose homeostasis

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