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10.1055/s-0043-1772836 91 PiA.JiangK.DingQ.LaiS.YangW.ZhuJ.et al (2021)

The Dana-Farber group conducted a phase I trial of 21 patients treated with CD25+ Treg-depleted DLI at two different dose levels, of whom four were in complete remission at the time of DLI after treatment with cytoreductive therapy for relapse ( 7 CD3+ cells/kg), one of six patients responded, while at the higher dose (3x10 7 CD3+ cells/kg), 60% experienced complete or partial response, with a one year overall survival rate in that cohort of 53%