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157 At the level of mitophagy, compounds such as docosahexaenoic acid (DHA) reduce lipid accumulation in adipocytes and improve mitochondrial function, supporting their potential utility in obesity management

High-pressure (e.g., greater than 80 to 100 cm H 2 0), long-duration (e.g., greater than 10 minutes) hydrodistension is associated with increased frequency of serious AEs (e.g., bladder rupture, sepsis) without a consistent increase in benefit