nac apap overdose mechanism glutathione The Metabolism of Acetaminophen and the Synthesis of 54 | Anesthesia Key
54 Anesthesia Key 5 Antidote: NAC (N acetylcysteine) NAC replenishes glutathione, restoring the ability to detoxify NAPQI. It's lifesaving if given early. Example: Hospitals use NAC as the standard treatment for APAP overdose. Full article: Paracetamol (acetaminophen) overdose and hepatotoxicity: mechanism, treatment, prevention measures, and estimates of burden of disease Acetaminophen Toxicity Poisoning
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