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Kernicterus: Epidemiological Strategies for Its Prevention through Systems-Based Approaches

Then that's a pretty clear indicator that you are raising your risk for that condition

Chronic stress may lead to alterations in the composition of membrane phospholipids, characterized by increases in phosphatidylcholine (PC) and phosphatidylethanolamine (PE), and a decrease in phosphatidylinositol levels (312)

Therefore, the two crucial mechanisms are that the transduction of PAR polymer to mitochondrial and the transfer of AIF from mitochondrial to nucleus to degrade chromatin