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In: Jon Lorsch (ed) Methods in enzymology

Soliman NS

These effects were replicated by using green-synthesized mannan-capped AuNPs, which showed receptor-mediated uptake and non-toxicity in mannose expressing (DC 2.4 and RAW 264.7) cells

CHAC1-mediated GSH degradation reduces S-glutathionylation of ARF6 at cysteine 90, thereby inactivating ARF6 and enhancing ferroptotic cell death ( Similarly, CHAC1 is upregulated in various kidney disease models (Ying et al., 2025)