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J Cancer Res Clin Oncol 149 , 1524915273 (2023)

These data were extracted from PanDDA, and structures were corrected and refined in a more classical manner using Buster 36 and Coot 35

However, the US Food and Drug Administration, or the FDA, has alerted the public to the dangers of combining kratom with other substances, noting that such interactions can lead to severe liver damage and even death