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PMCID: PMC10745386

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Across technical and preclinical contexts, these peptides are referenced strictly for educational and research purposes, with emphasis on analytical handling, standardized protocols, and pathway-focused investigation under appropriately controlled laboratory conditions

This subpopulation of LARS B cells shows a preference for Leu metabolism, which can be induced by a Leu diet to promote mitochondrial NAD + production and oxidative metabolism and recruit NAD + -dependent protein deacetylase SIRTUIN-1 (SIRT1) to participate in the regulation of LARS B cells