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Sica, A., Erreni, M., Allavena, P

Multiple triggers can tip the balance and cause melanin overproduction

The peptide also promotes polarization of macrophages from pro-inflammatory M1 phenotypes toward tissue-repairing M2 phenotypes, with treated macrophages showing 70% increased phagocytic activity for clearing inflammatory debris and 3-fold higher production of VEGF compared to untreated controls

Patterns that show up consistently: Cognitive Effects (Most Reported) Improved verbal fluency words come faster, conversations feel sharper Enhanced pattern recognition connecting ideas across domains more fluidly Better spatial memory navigation, visualization, and spatial reasoning Raw cognitive "horsepower" distinct from the mood/clarity effect of Semax/Selank