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7 A recent randomized, double-blind, placebo-controlled clinical trial to assess the efficacy of 3% propolis ointment (Herstat) in patients with a history of HSV-1 infection showed a mean healing time of 6.24 days, compared to 9.77 days in the placebo group, along with better pain relief

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In contrast, Phenylbutazone showed radioprotective effects in H2AX but failed to restore saliva secretion, possibly due to the long-term toxicity effects of corn oil used as a solvent (Fig