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Among them, RING finger E3s are crucial in maintaining the equilibrium between cell proliferation and apoptosis (11,12)

BMC Cancer 17 , 467 (2017)

For example, in the 1940s, doctors distinguished between allergic and non-allergic asthma, based on whether an allergen was likely involved in the asthma symptoms or if the asthma seemed to come from within.[ref] Since then, a better understanding of cellular processes and lung tissue has led to better classifications based on biomarkers