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Medications that work on 3 different receptors (GLP-1, GIP, and glucagon) are coming down the pipeline

Sikiric et al., 2020b), to induce a simultaneous healing, even in different tissues (and therefore the healing of diverse fistulas (Klicek et al., 2008

Nitric oxide signaling connects the three systems, regulating blood flow and inflammatory responses across muscular, digestive, and neural tissue simultaneously

Therefore, a holistic, de-medicalized, and systemic approach to health could move models of preventive and therapeutic strategies from simple associations rooted in empirical reductionism toward the appreciation of network-based models (179182)