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Although immunoglobulins have successfully been employed for the generation of actively targeted nanoparticles, their use is often hampered by the suboptimal characteristics of the resulting complexes

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The pharmacokinetic parameters, including substrate affinity for P-glycoprotein (P-gp) and inhibitory potential against cytochrome P450 (CYP450) enzyme isoforms, were predicted using support-vector-machine-based binary classification models embedded within the SwissADME framework