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doi: 10.1093/nar/gkab1128 50 SignorellA

Lipoic acid was found to effectively slow disease progression when administered either orally (87), intraperitoneally (88), or subcutaneously (89) to mice with experimental autoimmune encephalomyelitis (EAE), a model of multiple sclerosis

Contemp Oncol (Pozn) (2013) 17(1):15

As new skin cells generated under better antioxidant protection gradually replace older, damaged cells (a cycle that takes roughly 28-40 days), the cumulative effect becomes visible