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The discrepancy might suggest that the ETC dysfunction is secondary to other mechanisms that closely regulate mitochondria

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Injection site reactions (irritation, erythema, induration, pain, itching) in approximately 70% of subjects on drug and rarely on placebo more severe and/or prolonged after higher doses

Lu et al., 2001

Comparing the effect of Nigella sativa oil soft gel and placebo on oligomenorrhea, amenorrhea and laboratory characteristics in patients with polycystic ovarian syndrome, a randomized clinical trial