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Results Vitamin depletion screens in physiological culture medium identify riboflavin as an AML proliferative dependency Traditional culture medium is an imperfect recapitulation of physiological conditions, including supraphysiological levels of metabolites that enable rapid proliferation such as glucose and glutamine 21

One of the most common gaps is Vitamin B-12 a nutrient primarily found in animal-based foods

Glutathione is actually a very simple molecule our body makes it from three amino acids cysteine, glycine and glutamine

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