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PLoS ONE 11 , e0150949 (2016)

Systemic Injection Research demonstrates that BPC-157 exhibits both targeted local effects and systemic migration to areas of tissue damage

BDNF exerts its effects by binding to the TrkB receptor, activating downstream signaling pathways such as the PI3K/Akt and MAPK/ERK pathways, which promote cell survival and synaptic plasticity (Ma et al., 2013)