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Each step up delivered roughly 3 additional percentage points of weight loss: 1mg produced 8.7%, 4mg hit 15.2%, 8mg reached 21.1%, and 12mg topped out at 24.2%

DFX reaches peak blood levels within one and a half to 4 h after oral administration, with a half-life ranging from 8 to 16 h, and is generally administered once daily (Stumpf, 2007)

A study showed that just a 10 percent reduction in fat mass led to a 22 percent lower risk of heart failure with preserved ejection fraction and a 24 percent lower risk of heart failure with reduced ejection fraction, two subtypes of CHF

Ondansetron (Zofran) at 4-8mg is highly effective at blocking the brain signals that trigger nausea