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Notably, the in-vivo results were not uniformly positive: the peptide-copper complexes were associated with a slower reorganization of the tissue and a delayed activation of fibroblasts in that particular model rather than straightforwardly faster healing

Endocrine 50:405415 Kober K, Olshen A, Conley Y et al (2018) Expression of mitochondrial dysfunction-related genes and pathways in paclitaxel-induced peripheral neuropathy in breast cancer survivors

PloS Pathog (2016) 12(10):e1005972

However, excessive exposure to pesticides can lead to disruption of endocrine, mitochondrial (dys) function, and genetic and epigenetic modifications (Mostafalou and Abdollahi, 2013)