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10.1146/annurev.ecolsys.29.1.467 71 RizhskyL.DavletovaS.LiangH.MittlerR

In human cells, GDAP1 overexpression plays a cytoprotective role against oxidative stress

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In addition, within cells, a series of regulatory mechanisms are involved in redox processes, such as the Keap1/Nrf2 transcription factor, NF-B signalling, the MAPK pathway, PI3K-Akt cascades, and the AMPK-mTOR axis [6, 7]