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[26] Other research focused on carnitine and muscle weakness seems to support carnitines effects relating to muscle integrity

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However, a recently published phase II clinical trial using the iron chelator deferiprone reported that deferiprone was ineffective in newly diagnosed PD patients who had not previously received dopaminergic therapy and even worsened both motor and non-motor symptoms [177]

Thus, ALKBH5 supports stem cell self-renewal and multilineage potential by preventing excessive m6A methylation that would otherwise mark transcripts for degradation or altered splicing