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Notably, GHRH agonists have demonstrated effects in pancreatic -cell proliferation and metabolic function, suggesting their relevance to research into diabetes

The study monitored for erythema, itching, scarring, atrophy, telangiectasias, and post-inflammatory hyperpigmentation, none of which were observed

Published research suggests this sustained profile can blunt natural GH pulsatility over time and may reduce the somatotroph cells responsiveness to GHRH stimulation