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All simulations were conducted by GROMACS-2020 54 along with CHARMM36 force field 55,56

Furthermore, the high-resolution TEM (HR-TEM) image of ZFPG NPs showed that the crystal plane spacing of ZnFe 2 O 4 was 0.24 nm, which corresponded to the (222) crystal face of ZnFe 2 O 4 (PDF# 22-1012) with spinel structure

Similarly, pathways associated with oxidative phosphorylation and Ras signalling were dominant in the green module corresponding to myeloid cells, those associated with cytoskeleton proteins and MAPK signalling were dominant in the blue module corresponding to NK cells and pDCs and those associated with amino acid, lipid and steroid metabolism were dominant in the turquoise module corresponding to neutrophils