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Acta Med Scand 159:189194 Rowley JD, Golomb HM, Dougherty C (1997) The 1517 translocation: a consistent chromosomal change in acute promyelocytic leukaemia

This article systematically reviews the drug resistance mechanism of gemcitabine and explores the breakthrough direction of new drug delivery systems (liposomes, albumin nanoparticles) and combination therapy strategies (targeted drugs, immune checkpoint inhibitors)