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But theyre not yet proven to work, and there have been no large-scale clinical trials on humansnot even safety data

Without the mechanical action of the needles, the PRP would simply sit on the surface of the skin and be far less effective, but this combination ensures maximum absorption and triggers a powerful response

Potential side effects include: Skin irritation (with topical use) Increased risk of infections (with oral use) Headaches and fatigue Increased cholesterol levels Potential risk of blood clots (with long-term oral use) Patients should always consult a dermatologist before starting treatment with JAK inhibitors to weigh the benefits against possible risks