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Any claims about synergistic fat-loss effects from combining these agents are not supported by peer-reviewed clinical evidence

Nicotinamide N-methyltransferase (NNMT) is a cytosolic enzyme that catalyzes the methylation of nicotinamide using S-adenosylmethionine (SAM) as a methyl donor, producing 1-methylnicotinamide (1-MNA) and S-adenosylhomocysteine (SAH)

The adaptive effects of dietary fish and safflower oil on lipid and lipoprotein metabolism in perfused rat liver