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It can be caused by either exogenous or endogenous oxidants, and inflammatory and structural cells within the lungs can be both the target and source of oxidants [13]

70, 79, 80 (ii) the transduction of a MOMP-stimulatory signal via the pro-apoptotic BCL-2 family member BAK1, the PTPC component voltage-dependent anion channel 1 (VDAC1) and the BAK1 homolog BAX

HMGB1, a nonhistone nuclear protein abundant in mammalian chromatin, is involved in DNA transcription, repair, replication, and remodeling (Liu et al., 2010)