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The primary cilia of nerve cells can sense and respond to the changes of the local extracellular environment

In the sample with autoimmune hypothyroidism, the diagnosis had been made by endocrinologists at the Helsinki University Central Hospital, where the diagnostic criteria included elevated TPO antibodies, elevated TSH, reduced FT4, and ultrasound findings characteristic of autoimmune thyroiditis

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The pathophysiology of bacterial-endotoxin mediated tissue damage may involve the interplay of reduced host carnitine levels and pathogenic requirement of carnitine for growth and survival in the host [95]