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Notably, NNMT inhibition did not impact food intake in the DIO mice nor produce any overt signs of toxicity or adverse behavioral effects at the pharmacologically effective dose

Mov Disord Clin Pract 4:412415 Bhalsing K, Suresh K, Muthane UB, Pal PK (2013) Prevalence and profile of Restless Legs Syndrome in Parkinsons disease and other neurodegenerative disorders: a casecontrol study

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b) Daratumumab with PIs Bortezomib: An increasing level of DR5 and decreasing level of HLA-E enhance NK-mediated ADCC and reduce immune escape