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The Importance of Marine Omega-3s for Brain Development and the Prevention and Treatment of Behavior, Mood, and Other Brain Disorders

Although the mechanism(s) underlying NASH progression remain to be fully elucidated, accumulating evidence suggests that both oxidative stress and the pro-inflammatory cytokine tumor necrosis factor- (TNF) are critical contributors in this process 5

30 , 31 , 32 , 33 The direct interaction between GSTP1 and STAT3 can promote HCC progression, 8 and our previous study found that GSTP1 could be ubiquitinated by FBX8, thus inhibiting its function in promoting CRC proliferation, invasion and metastasis