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Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt

Gut-derived TMAO induces apoptosis by increasing intracellular mROS levels and further promoting NLRP3 assembly activation, with the underlying mechanism being the regulation of the intracellular mROS-NLRP3 axis to activate cytokinesis and release inflammatory factors, thus promoting DKD (Yi et al., 2023)