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Honghua Peng, [email protected] These authors have contributed equally to this work This article was submitted to Cancer Immunity and Immunotherapy, a section of the journal Frontiers in Oncology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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In addition, ROS generation by phagocytes, like macrophages and neutrophils, is also the cause of NP-induced oxidative stress (Horie and Tabei, 2021)