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TLR9 can interact with mtDNA in endosomes, leading to the initiation of an NF-B -dependent pro-inflammatory signaling pathway (178)

After 12--96 months (median 38 months) of ILP, 21 patients (29%) had thyroid surgery because of an unsatisfactory result..US-guided ILP results in a satisfactory long-term clinical response in the majority of patients with a benign solitary solid cold thyroid nodule, but further large-scale studies are needed (89.1)

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