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Arajo F, Martins C, Azevedo C, Sarmento B (2018) Chemical modification of drug molecules as strategy to reduce interactions with mucus

pylori infection was also identified as the strongest known risk factor for gastric cancer, as up to 90% of gastric cancer cases could be attributable to the infection

Therefore, this ROS generation strategy, not limited by the harsh tumor microenvironment (TME), such as low concentration of H 2 O 2 and hypoxia 25,26 , shows great potential in combination with immunotherapy