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Severe or prolonged B12 deficiency can lead to a range of neurological manifestations, including peripheral neuropathy, which may present as pain, paraesthesia (pins and needles), or altered sensation in the extremities

Elife 7, e38472

Caution: Copper-containing supplements may be unsuitable for people advised to limit copper

Based on our own experience and that of our department, we have incorporated PCT into a sepsis management algorithm, as an addition to clinical evaluation (Fig