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The size distribution of the exosomes was measured through nanoparticle tracking analysis using the NanoSight system (NanoSight, London, UK)

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Hydroxyl radical is one of the most reactive radicals with a short lifetime, about 10 8 10 9 s

It is particularly worth mentioning that the H 2 S response range of DCNP@PB is highly matched with the H 2 S concentration at the tumor site, which provides a strong guarantee for the specific detection of colorectal tumors in a complex physiological environment (Table 1)