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Int J Mol Sci 24(17):13297

This study provides an early report of the loss of glial cells within the PFC of patients with mood disorders, consistent with the hypothesized glutamate abnormalities in these disorders

Thus, observed potent induction of ferroptosis, GPX4-dependent novel suppression of mTOR pathway and DNA damage repair response in preclinical in vitro model of TC supports GPX4 targeting for therapeutic benefit in advanced therapy-resistant thyroid cancers