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Genome-wide association studies (GWAS) using large cohorts and dense datasets, including the Autism Genetic Resource Exchange, Simons Simplex Collection, Autism Genome Project, Autism Casecontrol, and Autism Center of Excellence, have revealed a myriad of genes implicated in autism [179]

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Based on this principle, Retrotope developed RT-001 (containing deuterated linoleic acid) and initiated its clinical trials to further verify its potential in treating related diseases (Brenna et al., 2020

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