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A 50% toxicity rate was reached at 0.94mmol/l in HepG2 and 0.68mmol/l in HepG2 ATP7B-KO cells

Fluorescent staining for casepase3/7 was done using CellEvent TM Caspase-3/7 Green Detection Reagent Kit (Thermo Fisher Scientific)

The principle of dose equivalence and the calculations are presented in further details in 72

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