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Exogenous delivery of H 2 S in a form of S -propargyl-cysteine in a special liposomal formulation, which leads to the slow release of the active gasotransmitter, had cardioprotective and anti-fibrotic effects by inhibiting the TGF-1/SMAD signaling pathway [235]

PA, a well-established copper chelating agent, has shown significant efficacy in the treatment of inflammatory bowel disease and Wilsons disease

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56 reported that intracellular reactive oxygen species and all amino acids, including glutamine, were increased in the NH 4 Cl-treated human astrocyte