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To this end, various structureactivity relationship (SAR) methodologies are employed, including, but not limited to, site-directed mutagenesis, rational computational design, high-throughput screening of synthetic peptide libraries, template-guided structural refinement, and mechanism-driven design strategies inspired by natural biological processes

found that GSH deficiency was involved in functional and structural cardiac abnormalities of patients with cardiac diseases

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They order appropriate baseline labs to evaluate blood sugar, kidney function, liver health, and cholesterol