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Results NF-B was involved in the expression of EAAT3 In our previous study, we reported that GPRC5A deficiency leads to the induction of EAAT3, facilitating glutamate recycling and GSH biosynthesis

Specifically, one double-blind trial in 140 patients with chronic schizophrenia, described by the Cochrane Collaboration as a high quality trial that measured clinically-useful outcomes (Positive and Negative Syndrome Scale [PANSS] and Clinical Global Impression [CGI]) over a longer period of time [145], compared adjunctive NAC versus placebo [146]

10.1038/s41392-024-01916-y 37 DuanY.DharA.PatelC.KhimaniM.NeogiS.SharmaP.et al (2020)

10.2174/1570159x13666160502153022 [DOI] [PMC free article] [PubMed] [Google Scholar] Sikiric P., Seiwerth S., Rucman R., Turkovic B., Rokotov D