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doi: 10.1007/s00401-021-02347-7 90 JenkinsNCRaoGEberhartCGPedoneCADubucAMFultsDW

Common side effects reported with retatrutide include: Nausea, vomiting, and diarrhoea (most frequent, particularly during dose escalation) Decreased appetite Constipation Injection site reactions Mild increases in heart rate Cagrilintide has demonstrated a generally well-tolerated profile, with gastrointestinal symptoms also being the most commonly reported adverse effects