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Ivanov et al

The mobile phase comprised methanol and water at a ratio of 98:2 by volume, and an equal elution method was selected

If neurological symptoms are present, treatment is more intensive: 1 mg on alternate days until no further improvement occurs, then maintenance doses of 1 mg every 2 months

Research on treatment for period pain showed that B12 supplementation, alongside fish oil, reduced period pain due to its inhibiting effects on prostaglandin production