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Nivolumab for recurrent squamous-cell carcinoma of the head and neck

The high affinity of GHK for copper(II) is a defining feature of the molecule

40: 3377-3380 Hoffmann B, Konrat R, Bothe H, Buckel W, Krutler B

Reaction of the active site Cys with H 2 O 2 is catalyzed by a mechanism which stabilizes the transition state and promotes leaving group departure by providing a proton relay