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Patients suffering from PD and characterized by slowed transit of the intestine may consequently need to receive higher amounts of L-DOPA (Fasano et al., 2013

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Gaudette BT, Jones DD, Bortnick A, Argon Y, Allman D

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The concept was initially proposed in 2013 (13) and was updated in 2023 (14)

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doi:10.1507/endocrj1954.33.405

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