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Ren et al., 2011)

Toxicology 24, 211222

Moreover, low-dose spironolactone in PCOS rats reduces the oxidative stress markers (MDA) and inflammatory biomarkers such as NF-kB, TNF-, and IL-6 (241)

Given the critical role of GLS in cancer metabolism and tumor progression, inhibiting GLS and targeting its breakdown have emerged as promising strategies for cancer treatment