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From these data, k cat of the protein was found to be 2500 min 1 and the corresponding k cat / K m is 3.36 10 6 min -1 M 1 (Table 3 and Table S1)

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It is primarily used for perioperative pain, although the clinical trial data to support this use is limited at best.It is also used for acute injury, colic, cancer pain, other acute/chronic forms of pain and high fever unresponsive to other agents

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