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Systemic L-buthionine-S-R-sulfoximine administration modulates glutathione homeostasis via NGF/TrkA and mTOR signaling in the cerebellum

7a, cg), indicative of a gradual dependence of mitochondrial metabolic reprogramming in breast cancer progression

These findings are summarized in a Cochrane review (238) including one study with high-dose Zn intake [(305), 10 mg/day] and 4 studies with low (currently recommended) dose were included (63, 64, 306, 307)