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The protective effects of ALDH2 are mediated by several mechanisms: ALDH2 downregulation activates caspase-associated pathways, which subsequently promote necroptosis induction (120)

Relevance of Neuroinflammation and Encephalitis in Autism

The peptide achieves this by enhancing tight junction formation between keratinocytes and stimulating the expression of aquaporins, specialized water channel proteins that regulate moisture distribution within the epidermis